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Human KEAP1 / INRF2 Protein
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Human KEAP1 / INRF2 Protein
Human KEAP1 / INRF2 Protein
Human KEAP1 / INRF2 Protein from Sino Biological, Inc.
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Citations:
(5)
Supplier Page
Supplier Page from
Sino Biological, Inc. for
Human KEAP1 / INRF2 Protein
Description
A DNA sequence encoding the human KEAP1 (Q14145) (Gln2-Cys624) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus
Product Specs
Company Info
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Reviews
Product Specs
Item
Human KEAP1 / INRF2 Protein
Company
Sino Biological, Inc.
Price
Supplier Page
View Company Product Page
Catalog Number
11981-HNCB
Conjugate/Tag
N-cleavage
Purity
> 85 % as determined by SDS-PAGE
Type
Recombinant protein
Molecular Weight
The secreted recombinant human KEAP1 consists of 625 amino acids and predicts a molecular mass of 69.7 KDa. The apparent molecular mass of the protein is approximately 64 KDa in SDS-PAGE under reducing conditions due to glycosylation
Species
Human
Molecule Name
KEAP1
Source/Expression System
Baculovirus-Insect Cells
NCBI Full Gene Name
kelch like ECH associated protein 1
NCBI Gene Aliases
INrf2, KLHL19
Format
Lyophilized from sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 7.4
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Sino Biological, Inc.
1400 Liberty Ridge Drive
Suite 101
Wayne
,
PA
19087
United States
Phone
: 215-583-7898
Fax: 267-657-0217
Email: marketing@sinobiological.com
Company Profile
Website:
http://www.sinobiological.com/
Citations (5)
(1)
Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly
Free Radical Biology and Medicine
August 1, 2023
Roslin J. Adamson, N Connor Payne, Sergio G. Bartual, Ralph Mazitschek, Alex N. Bullock
and FLAG tags cleavable by TEV protease. Full-length
KEAP1
was purchased from
Sino Biological
(cat#
11981-HNCB
). 2.2
Protein expression
and
purification
Bacterial protein expression was performed in BL21(DE3)-pRARE2
(2)
A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
Cell chemical biology
August 18, 2022
Payne NC, Maksoud S, Tannous BA, Mazitschek R.
formation between full-length, wildtype
Keap1
and individual recombinant bromodomains
Keap1
(tag-free;
11981-HNCB
;
Sino Biological
) was diluted to 40 nM in
assay
buffer (supplemented with 1 mM DTT) containing 40 nM
(3)
Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome
Journal of medicinal chemistry
March 24, 2022
Dai Z, An LY, Chen XY, Yang F, Zhao N, Li CC, Ren R, Li BY, Tao WY, Li P,
et al
.
(4)
Bright and stable luminescent probes for target engagement profiling in live cells
Nature chemical biology
November 1, 2021
Payne NC, Kalyakina AS, Singh K, Tye MA, Mazitschek R.
(5)
GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma
Science signaling
August 18, 2020
Hayashi M, Guida E, Inokawa Y, Goldberg R, Reis LO, Ooki A, Pilli M, Sadhukhan P, Woo J, Choi W,
et al
.
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Human KEAP1 / INRF2 Protein from Sino Biological, Inc.
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